Treat dermatological problems the easy way with S-I-S Science from Virbac.
Virbac, pioneer in veterinary dermatology, offers a range of skin products tailored to individual problems to improve the quality of life for pets and their owners.
INTRODUCING S-I-S: SKIN INNOVATIVE SCIENCE™

S-I-S SKIN INNOVATIVE SCIENCE™ is the name for the combination of 2 technologies from Virbac working together to help maintain microbial balance and help the skin get better.

Defensin Technology and Glycotechnology both work to enhance the two essential roles of the skin: To be a physical barrier and to provide immune defence.

Anti-microbial peptides (AMPs) or Defensins are always present in the skin and are an essential component of the skin’s response to infection and trauma. They kill microbes such as bacteria and yeast,1,2 stimulate healing and recruit immune system cells such as macrophages and T-cells.

Glycotechnology uses a range of sugar-like compounds called glucids, specifically mannose, rhamnose, galactose and alkyl polyglucoside (APG).

In the same way that cells use proteins and lipids to signal to each other, they also use sugars. Glucids can block the ability of microbes to attach to the skin.

The Glycotechnology in S-I-S shampoos can reduce the adherence of the bacteria Staphylococcus pseudintermedius7 and Pseudomonas aeruginosa8 by over 50%, and the adherence of the yeast Malassezia pachydermatis9 by over 40%.

Glycotechnology also modulates the immune response and skin inflammation to reduce itching and discomfort. This is due to how the glucids interact with cytokines and membrane bound receptor proteins.

To aid the body's ability to defend itself, the plant extracts in S-I-S shampoos from Boldo3 and Meadowsweet4 stimulate the production of AMPs by the skin.5 The Defensin Technology in S-I-S can reduce microbial load by 76%.6
SHAMPOO YOUR DOG THE EASY WAY
SHOWER, DON'T BATHE.
 
For medicated shampoo to be effective, it has to be present on the skin for some time. Bathing your pet will usually dilute the shampoo down until it is not effective.
USE WARM RUNNING WATER.
 
Not too hot, not too cold – to thoroughly wet the skin and coat. The running water can be poured over your pet with a cup or jug, but is best done with a hand-held shower head or attachment. Use a sponge around the face.
MASSAGE SHAMPOO IN WELL.
 
Once your pet is wet, use enough to get good lather, by applying the shampoo to several points on the body. This step is to get your pet CLEAN. Take care around your pet’s eyes! Then rinse well.
SHAMPOO AND LATHER AGAIN.
 
This time let the suds stand so the active ingredients can soak in, especially for medicated shampoos, ideally for about 10 minutes – aim for at least three minutes. Massage the shampoo in while you are waiting.
RINSE THOROUGHLY.
 
Do not leave any residue of the suds on the skin.
DRY WELL.
 
Small pets that can get a chill and pets with long coats may need a hair dryer: use it only on a low setting as it is easy to overheat them. Comb or brush the hair if required.
CATS CAN ALSO BE SHAMPOOED
Cats can need medicated shampoos to treat disease and maintain skin and coat health. With warm water and gentle encouragement most cats will tolerate shampooing well.

A MILD SHAMPOO FOR NORMAL, DRY AND/OR ITCHY SKIN.
 

Epi-Soothe® ShampooEpi-Soothe® Shampoo uses the power of natural oatmeal, famous for its soothing and deep cleansing properties. Colloidal oatmeal helps the skin retain its moisture, relieves itching and can help reduce the need for corticosteriods in some cases.

Epi-Soothe® Shampoo

 

Superior soothing, cleansing and moisturising action for normal, itchy and dry skin due to the presence of colloidal oatmeal, and Skin Innovation Science.™

FREQUENTLY ASKED
QUESTIONS
 
WHY SHOULD I SHAMPOO MY PET?
  • To remove the pollen and debris that can stimulate allergic reactions.
  • To help replenish the oils and moisture of the skin barrier.
  • To deliver medications contained in the shampoo to wide areas of skin.
WHY SHOULD I USE A SHAMPOO SPECIFICALLY
DESIGNED FOR PETS?
  • Cats and dogs have very different skin to us – it is much thinner and less acidic.
  • Veterinarians recommend pH balanced skin care products especially formulated for cats and dogs’ skin, such as the Virbac range.
  • Using products not designed for pets can cause or inflame problems like dryness and itchiness by stripping essential natural oils.
HOW OFTEN SHOULD I SHAMPOO MY PET?
  • Normal skin: weekly to fortnightly.
  • Special conditions (e.g. infected skin): check with your vet.
FOR GREASY, SMELLY SKIN THAT HAS BECOME INFECTED.
 

Washing with Sebolytic® will help remove excess oils and repair damage to the skin. Regular use will make your pet’s coat shiny, healthy and smell fresh.

Sebolytic® Shampoo
 

  • Softens and removes skin crusts.
  • Adjusts skin cell renewal.
  • Maintains microbial balance.
  • Reduces itching.
  • Regulates sebum production.
  • SIS to prevent microbe adhesion and stimulate natural defences.
  • Can be used in cats.
WHAT IS SEBORRHEA?
 

Seborrhea is a condition that shows as a greasy and possibly smelly coat. Some dogs have an inherited tendency to be greasy, or seborrhea can be caused by allergies to things such as pollen or food.

Seborrhea can be oily (olesosa) or dry (sicca). Pets with seborrhea oleosa can develop waxy substance that coats their fur or clumps in their ears. Seborrhea sicca causes flaky skin, like dandruff. Pets can suffer from both types of seborrhea at the same time.

The affected skin can be very itchy, causing the pet to scratch excessively, which can lead to hair loss, raw weepy wounds, and  secondary infections.

Sebolytic® is the ideal product to treat greasy smelly skin and coat.

Use Sebolytic® two or three times each week. Treating for up to 4 weeks may be necessary to control some skin disorders.

FOR NORMAL, DRY
AND/OR ITCHY SKIN.
 

Pyoderm® treats pyoderma – infected skin. Pyoderma can present as pustules, crusts and scale. Pyoderm® S is a medicated shampoo that treats malassezia skin infections and aids in the treatment of Staphylococcus skin infections.

Pyoderm® S Shampoo

 

The 3% chlorhexidine formulation has been proven to treat a wide range of bacterial and yeast skin infections.

Non-Ionic Spherulites® in Pyoderm® S allow penetration of the chlorhexidine into the deeper layers of the skin.

Chitosanide is a protein which promotes healing and hydrates the skin. This is important for patients that require frequent and long term shampooing.

WHAT IS ATOPY?
 

Anyone can suffer from allergies: dogs and cats just as much as humans. An allergy is where the body responds to innocuous materials as if they are invading microbes. Allergies can be to bites from insects such as fleas, to food and drink, to pollen and dust, even to metals. When a dog has a reaction on their skin to inhaled allergens (material that causes an allergic reaction) that is referred to as canine atopic dermatitis, or atopy.

Because so many allergens that set off atopy are ubiquitous, like dust mite dander, avoiding the cause is virtually impossible. Therefore management of atopy is focused on treatment and management of symptoms.

Skin damaged by atopy, and the trauma of scratching, is highly prone to secondary infection.

Soothing the skin, repairing damage, reducing itchiness, along with antihistamines and steroids are the best way to control atopy. Talk to your vet about what treatment is best for your pet.

CLEANS, SOOTHES & MOISTURISES SENSITIVE AND ITCHY SKIN.
 

Specifically designed to meet the needs of dogs and cats with skin barrier imbalance, Allermyl® shampoo is a unique microemulsified formulation which combines ingredients that help to maintain skin barrier integrity and natural microbial balance.

Allermyl® Shampoo

 

S-L-C™ technology improves skin barrier protection against environmental aggressions with moisturising and soothing effects.

S-I-S™ technology improves skin vitality with microbe anti-adhesive effects (Glycotechnology) and stimulation of natural skin microbial defence (Defensin Technology).

Makes the most of the latest research to restore the skin barrier and return softness and vitality to sensitive and irritated skin.

SKIN LIPID COMPLEX™ TECHNOLOGY
 
 

S-L-C is a combination of cholesterol, ceremide and fatty acids to nourish and moisturise the skin.10

These essential ingredients are present in a balanced ratio. These lipids penetrate the skin and are used by skin cells to build the lamellar bi-layers.11 Lamellar lipids are especially low in dogs suffering from atopic dermatitis.

The use of S-L-C in these dogs can more than double the amount of intercellular space filled by structured lamellar lipids in the lower stratum corneum,12 where skin cells grow. This reinforces the skin’s barrier function and decreases water loss from the skin.

THE VIRBAC FAMILY OF SKIN PRODUCTS

CORTAVANCE® A powerful steroid spray for controlling allergic and inflammatory conditions. The active ingredient is metabolised in the skin minimising side-effects from steroid use.

EPI-OTIC® A soothing ear cleaner used to maintain hygiene, prevent ear infections, and to help the effectiveness of topical ear medications.

EASOTIC® A strong prescription ointment to quickly treat ear infections. Comes in an easy to use airless pump for accurate dosing.

IMFLAMOL® A strong combination ointment with a soothing steroid, an antibiotic and healing and moisturising ingredients.

RILEXINE® A tasty and easy to administer first-line therapy antibiotic. Particularly useful for skin, bladder, respiratory and digestive infections.

Cortavance®, EasOtic®, Inflamol® and Rilexine® are Registered Veterinary Medicines. Available only under Veterinary Authorisation. ACVM No's A10060, A10305, A4600 and A9159.


Pyoderm® S Shampoo, ACVM No. A9396. (1) AFSHAR M, L.GALLO R. Innate immune defense system of the skin. Vet Dermatology, 2013, 24: 32-e9. (2) SANTORO D., MADDOX C. Canine antimicrobial peptides are effective against resistant bacteria and yeasts. Vet. dermatol. 2014, 25:35-e12. (3) Peumus boldus.(4) Spiraea ulmaria. (5) MARSELLA R. et al. Evaluation of the in vitro effect of plant extracts on the production of antimicrobial peptides and inflammatory markers in canine keratinocytes: a pilot study. Veterinary Dermatology, 2013, 24:295-309. (6) SANTORO D. et al. Evaluation on the effects of 0.1% Peumus boldus leaf and Spiraea ulmaria plant extracts on bacterial colonisation in canine atopic dermatitis: a preliminary randomised, controlled, double-blinded study. Accepted for communication at the WCVD 2016, Bordeaux, France. (7) MCEWAN N. A. et al. Sugar inhibition of adherence by Staphylococcus intermedius to canine corneocytes. Vet Dermatology, 2006, 17(5): 358. (8) MCEWAN N. A. et al. Monosaccharide inhibition of adherence by Pseudomonas aeruginosa to canine corneocytes. Vet Dermatology, 2008, 19: 221-225. (9) MCEWAN N. A. et al. Sugar inhibition of Malassezia pachydermatis to canine corneocytes. Vet Dermatology, 2007, 18(3): 187-188. (10) MARSELLA R. et al. Investigations on the effects of a topical ceramides-containing emulsion (Allerderm® Spoton) on clinical signs and skin barrier function in dogs with topic dermatitis: a double-blinded, randomised, controlled study. Intern J Appl Res Vet Med., 2013, 11 (2) 2110-116. (11) PIEKUTOWSKA A. et al. Effects of a topically applied preparation of epidermal lipids on the stratum corneum barrier of atopic dogs. J Comp. Path. 2008, 138 :197-203. (12) POPA I. et al. The lipid alteration in the stratum corneum of dogs with atopic dermatitis are alleviated by topical application of a sphingolipid-containing emulsion. Clinical and Experimental Dermatology, 2011, 1-7.