Lepto 4-Way™

Leptospirosis vaccine for calves and adult cattle

  • Cattle
  • Vaccine

Lepto 4-WayTM is an inactivated leptospirosis vaccine developed in response to the emergence of the Tarassovi-like serovar, ‘Pacifica’. As well as Tarassovi, the vaccine also contains serovars Hardjo, Copenhageni and Pomona - serovars that have been identified to cause disease in livestock and humans in New Zealand.

Recent epidemiological studies1,2 suggest Pacifica’s prevalence is high in dairy herds in New Zealand, leading to a disproportionate disease incidence and emotional toll on dairy farmers and their families.

  • No added adjuvant, meaning reduced injection site reactions, ease of syringeability and minimal settling in packs & injectors
  • Able to be used for 30 days after the pack is opened
  • Can be used in at-risk calves from 4 weeks of age


  • Cattle should be given 2 ml in the upper neck by subcutaneous injection.
  • A further dose of 2 ml should be given four to six weeks later.
  • All animals require a single 2 ml booster each 12 months.


  • Milk: Nil
  • Meat: Nil


Available in 500 ml plastic pillow packs, and clinic packs of 20 x 500 ml plastic pillow packs.


To learn more about Lepto 4-WayTM, download the Product Profile and speak with your vet.

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Lepto 4-WayTM is a Restricted Veterinary Medicine. Available only under Veterinary Authorisation. Registered pursuant to the ACVM Act 1997, No. A012030.


1. Y. Yupiana, E. Vallee, P. Wilson, J. Collins-Emerson, J. Weston, J. Benschop, C. Heuer. Emerging Leptospira strain poses public health risk for dairy farmers in New Zealand: Preventive Veterinary Medicine, Volume 170, 2019.

2. DA. Wilkinson, M. Edwards, C. Shum, M. Moinet, N. Anderson, J. Benschop, S. Nisa.  Molecular typing of Leptospira spp. in farmed and wild mammals reveals new host-serovar associations in New Zealand: 2023 Conference Proceedings of the Epidemiology, Food Safety, Animal Welfare and Biosecurity Branch of the NZVA, p13-14.

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