Safe and effective treatment option for unwanted mating and pregnancy in dogs
Alizin® is the most safe and effective treatment option for unwanted mating and pregnancy in dogs, and it can be used up to 45 days after mating. Alizin® contains aglepristone which is a synthetic progesterone antagonist, meaning that it attaches to, and binds tightly to progesterone receptors on the uterus without activating the receptors. This blocks the effects of progesterone. Progesterone is required to allow embryos to implant into the wall of the uterus and is required to maintain pregnancy.
When progesterone is blocked by Alizin®, fertilised ova will not be able to implant and so pregnancy is not established. Alizin® will also stop the maintenance of the appropriate environment in the uterus and pregnancy will be lost.