Reproduction and Contraception

Alizin®

Safe and effective treatment option for unwanted mating and pregnancy in dogs

  • Dog
  • Injectable
    Injectable

Alizin® is the most safe and effective treatment option for unwanted mating and pregnancy in dogs, and it can be used up to 45 days after mating. Alizin® contains aglepristone which is a synthetic progesterone antagonist, meaning that it attaches to, and binds tightly to progesterone receptors on the uterus without activating the receptors. This blocks the effects of progesterone. Progesterone is required to allow embryos to implant into the wall of the uterus and is required to maintain pregnancy. 

When progesterone is blocked by Alizin®, fertilised ova will not be able to implant and so pregnancy is not established. Alizin® will also stop the maintenance of the appropriate environment in the uterus and pregnancy will be lost.

  • Very safe with an excellent safety profile
  • When given before 21 days after mating, the treatment is 99% effective
  • When given between 21 and 45 days after mating the treatment is about 95% effective

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    Frequently Asked Questions
    • I am a veterinarian however I do not live in New Zealand. How can I purchase Alizin?
    • I am a dog owner interested in purchasing Alizin however I do not live in New Zealand. What should I do?